What is Nanomedicine?

What is Nanomedicine?- Daily Techno Review

Nanomedicine is the medical application of advances in nanotechnology. Nanoscience in the field of physics and chemistry has led to the development of methods and objects that are unique to date. The same is true in the field of biology, with nanomedicine and nanobiotechnology. After DNA sequencing, one of the major challenges today is to elucidate the role that DNA modifications play in the regulation of gene expression. In this article we discuss about Nanomedicine and its uses.

DNA Biochips, Cell Chips and Protein Chip:

A set of techniques has been developed: DNA biochips, of course, but also cell chips and protein chips, to analyze at the smallest scale the cells themselves as well as the proteins.

What is Nanomedicine?- Daily Techno Review

Another aspect is the creation of new objects such as functionalized nanoparticles that allow, for example, the in vitro and in vivo biological labeling of other biological objects.

Nanomedicine:

On a small scale, molecular motors, ATP synthase, allow to realize signaling, endocytosis or phagocytosis machineries. Aptamers, foldable nanostructures, can exert a catalytic activity or interact specifically with proteins or small molecules.

Beyond these nano-bio-objects, as in other fields, specific techniques in nanomedicine and nanobiotechnology have evolved or been developed:

What is Nanomedicine?- Daily Techno Review
  • Surface Plasmon Resonance (SPR), to measure molecular interactions;
  • PCR (Polymerase Chain Reaction), real time allowing the quantification of nucleic acids;
  • near field microscopies such as SNOM for topographic information coupled with optical information of biological surfaces;
  • AFM, for a real cellular and molecular imaging of these same surfaces;
  • Micromanipulations (micropipettes), for the study of forces between individual molecules (adhesion, membrane fusion);
  • patch-clamp” technology, allowing direct access to the activity of the protein- channel leading to the study of bio-membranes at the molecular level.

Vectorization for Nanomedicine

Just like the field of nano-objects or “nano-resolved” methods, the field of biological applications is vast: that of vectorization is one of the most important. Using nanometric objects such as nanoparticles or liposomes, it is possible to functionalize, on a very small scale, objects that ensure stealth and targeting thatcan treat disease as close as possible to the pathogenic cells for applications in parasitology, vaccination or cancerology.

What is Nanomedicine?- Daily Techno Review

All these advances augur well for the development of nanomedicine only nano-invasive, where the disease will be detected at its closest periphery and then treated at the smallest scale.

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